Lead, APEX Strategy and Operations

Flagship Pioneering, Inc. · Cambridge, MA USA

  • Senior
  • Full-time
  • $128,000 – $203,500
  • Posted 2026-11-09
  • Confirmed live on 10 November 2026

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Job description

Flagship Pioneering invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond.

What sets Flagship apart is our ability to unite life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs that generate exceptional value for people and the planet.

Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE's “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company's annual list of the World's Most Innovative Companies.

Position Summary

Flagship Pioneering is seeking a highly motivated Lead, Strategy & Operations to join our growing APEX Group. Flagship undertakes dozens of complex, value-oriented transactions at any given time — including joint ventures and partnerships, mergers and acquisitions, initial public offerings, licensing and collaborations, global fundraising, and business and corporate development initiatives. All of the activities associated with transactions at Flagship are led by a cross-disciplinary group, referred to internally as the “APEX Group.” APEX is an acronym for “Acquisitions, Partnerships, Equity and eXecution.”

Where other roles on the team own the substance and negotiation of individual transactions, this role owns the engine that keeps the whole group running: the operating cadence, the pipeline visibility, the processes, and the follow-through that let a small, senior team execute a high volume of complex deals without dropping anything. This is an outstanding opportunity for a highly organized, strategic operator who wants close exposure to Flagship's Executive Leadership Team and to some of the most innovative transactions in life sciences, without needing to come from a deal or legal background.

This individual will partner closely with APEX leadership and coordinate across Flagship's Executive Leadership Team, Business Development, Corporate Development, Legal, Finance, IP, and portfolio company leadership to keep strategic priorities, transactions, and initiatives moving on schedule.

Responsibilities

• Drive APEX's operating cadence, priority-setting, and internal communications on behalf of group leadership.

• Own end-to-end project management across the APEX transaction pipeline: tracking status, milestones, risks, dependencies, and resourcing across dozens of concurrent transactions.

• Design and run the group's strategy and operations processes, including planning cycles, goal-setting, budget and headcount planning, and performance reporting.

• Build and maintain dashboards, trackers, and reporting that give APEX and Flagship leadership real-time visibility into deal pipeline, resourcing, and outcomes.

• Develop and maintain playbooks, templates, and best practices to standardize and scale transaction execution across the group.

• Coordinate cross-functionally with Business Development, Corporate Development, Legal, Finance, IP, and portfolio company leadership to remove bottlenecks and keep initiatives on track.

• Prepare materials and drive agendas for APEX leadership meetings, offsites, and updates to Flagship's Executive Leadership Team and Board.

• Lead special strategic projects and process-improvement initiatives on behalf of APEX leadership.

• Manage onboarding, training, and knowledge-sharing for new APEX team members.

• Identify inefficiencies in transaction execution and drive practical solutions to improve speed and quality.

Qualifications & Experience

• Bachelor's degree required; MBA or other advanced degree a plus.

• 8+ years of experience in project or program management, business operations, strategy, or management consulting; prior exposure to life sciences, biotech, or complex transactions is preferred but not required.

• Proven ability to manage complex, multi-workstream initiatives across cross-functional, senior stakeholder groups in a fast-paced environment.

• Strong analytical and reporting skills, with experience building and maintaining dashboards, trackers, and executive-ready materials.

• Excellent executive presence and written/verbal communication skills, with experience preparing materials for and advising sen

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