Vice President, Portfolio Sales and Field Team

Revolution Medicines · Remote (United States)

  • Senior
  • Full-time
  • $294,000 – $367,000
  • Posted 2026-04-29
  • Confirmed live on 25 September 2026

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Job description

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity:

The Vice President, Oncology Sales will lead the design, build, and execution of a high-performing, national oncology sales organization supporting Revolution Medicines products/services to the oncology communityg. Reporting to the SVP of US Marketing & Field, the VP will be responsible for creating and scaling a best-in-class sales organization, ensuring successful product launches, and driving sustained revenue growth. This leader will combine strategic vision with operational rigor, leveraging deep oncology expertise and cross-functional collaboration to position the organization for long-term success.

Key Responsibilities:

Organizational Build & Leadership

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Architect and execute the build-out of a national portfolio oncology sales organization, including hiring, onboarding, and development of regional leaders, account directors, and sales representatives.

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This will include nurse educator and other field facing roles or functions including sales operations and training.

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Establish organizational structure, roles, and deployment strategy aligned to brand objectives and market dynamics.

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Foster a high-performance culture grounded in accountability, collaboration, innovation, and patient-centricity.

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Develop leadership bench strength through coaching, succession planning, and talent development initiatives.

Strategic & Commercial Leadership

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Define and execute the national sales strategy across oncology indications, ensuring alignment with corporate objectives and brand strategies.

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Lead all aspects of product launch readiness and execution, including field deployment, targeting, messaging alignment, and performance tracking.

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Partner with Commercial Leadership Team to shape enterprise-wide strategy, providing field insights and actionable recommendations.

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Drive achievement of all revenue and performance targets, ensuring consistent delivery against quarterly and annual goals.

Sales Operations & Execution Excellence

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Oversee development and execution of key commercial levers including: Forecasting and demand planning, Incentive compensation design, Territory alignment and targeting, Performance analytics and reporting, Training and capability development programs.

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Ensure disciplined execution of business plans and continuous optimization based on market feedback and data insights.

Key Account & Market Engagement

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Lead strategy and executive engagement for top national accounts, including major health systems, IDNs, oncology networks, and GPOs.

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Oversee development and execution of strategic account plans that drive access, adoption, and long-term partnerships.

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Serve as a senior external representative of the company with key stakeholders and decision-makers.

Cross-Functional Collaboration

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Partner closely with Marketing, Market Access, Medical Affairs, Commercial Operations, and Training to ensure aligned execution.

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Lead cross-functional initiatives to address business challenges, optimize launch performance, and enhance customer experience.

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Act as the “voice of the field” to inform brand strategy, pipeline planning, and organizational priorities.

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Shape clinical development planning and prioritization.

Compliance & Governance

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Ensure all field activities adhere to regulatory, legal, and compliance standards.

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Model and reinforce ethical leadership and decision-making across the organization.

Required Skills, Experience and Education:

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Bachelor’s degree required; advanced degree (MBA, PharmD, PhD) preferred.

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25+ years of biopharmaceutical industry experience, including significant oncology leadership.

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Proven track record of building and scaling sales organizations, preferably in small-to-mid-size biotech environments.

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Demonstrated success leading oncology product launches, including oral oncolytics.

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Prior leadership of second-line leaders (e.g., regional directors managing managers and reps).

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Deep expertise in oncology market dynamics, including GI, NSCLC preferred.

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Strong strategic, analytical, and operational leadership capabilities.

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Experience working in highly cross-functional, matrixed organiz

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