Automation Engineer

Natera · Boulder, CO

  • Senior
  • Full-time
  • $95,800 – $110,000
  • Posted 2026-10-05
  • Confirmed live on 15 October 2026

Apply at Natera

Job description

Location: On-Site in Boulder, CO (Foresight Dx business unit, a Natera company)

Shift: Monday-Friday, 7:30/8am start time

Foresight Diagnostics is a molecular diagnostics company pioneering non-invasive cancer detection through highly sensitive, cell-free DNA-based liquid biopsy technologies. Our proprietary methods - originally developed at Stanford University - are designed to detect smaller tumors earlier and enable more personalized treatment strategies for patients with cancer.

We sit at the intersection of molecular biology, bioinformatics, and next-generation sequencing (NGS), and we translate rigorous science into clinically meaningful solutions. Following our acquisition by Natera, we now combine the agility of a mission-driven startup with the scale and resources of a global leader in cell-free DNA testing. It’s an exciting moment to join us.

Headquartered in Boulder, Colorado, our team operates in a high accountability, collaborative environment where quality and continuous improvement aren’t just values - they’re how we work every day.

POSITION SUMMARY:

The Lab Automation Engineer at Foresight Diagnostics will be responsible for supporting the development and continuous improvement of Foresight’s laboratory automation function as well as providing first line support for troubleshooting methods in the CLIA lab. As the business life cycle evolves to vertically integrate manufacturing, this role will support the development and implementation with transition to the tech transfer functions within the organization. This position will collaborate cross functionally to deliver on business objectives with the intention of cross functional integration and operational scaling. This is a full-time position working 7:30 AM to 4:00 PM Monday to Friday, but may require the flexibility to work diverse schedules, including weekends, and holidays.

PRIMARY RESPONSIBILITIES:

• Effectively deliver to project deadlines, on time and on budget, with adherence to applicable quality and regulatory requirements.

• Iterate on processes to drive continuous improvement with prioritization managed through the application/interpretation of KPI results.

• Collaborate with laboratory leads to align on automation requirements and develop workflows and instrument methods for laboratory optimization and software integration.

• Regularly perform preventative maintenance and inspections on Foresight’s automated systems to ensure reliable functionality.

• Execute major and minor repairs or coordinate with vendors for more complex repairs.

• Collaborate with Laboratory Operations to develop SOPs and training programs to enable successful tech transfer of new technology/workflows to the laboratory teams for production use.

• Work cross-functionally with Operations, Finance, and laboratory teams as necessary to properly forecast the number of automation instrumentation needed to meet volume demand, plan for and propose upgrades to the Foresight’s automation solution.

• As needed, perform maintenance to ensure operational capacity never impacts Foresight’s ability to successfully deliver on time results.  

• Ensure effective resource utilization, planning and execution of people, process, and products in alignment with corporate objectives and volume projections across cross-functional teams.

• Implement laboratory processes that are compliant with appropriate regulations, to include but not limited to GxP, ISO, CFR, CAP/CLIA, NYSDOH.

• Guide troubleshooting and resolution of incident reports and CAPAs while driving continuous improvement

QUALIFICATIONS:

• 5+ years engineering experience supporting laboratory environments.

• A bachelor’s degree: BA/BS. An advanced degree, such as a Ph.D. or Masters degree preferred.

• Additional technical training would be a plus with an understanding of molecular biology and genomics.

• Working knowledge of liquid handling platforms such as Hamilton STAR line and Agilent Bravo preferred

• Proven ability to deliver actionable results to complex problems.

• Strong organizational skills with an understanding of scaling and capacity planning.

• Advanced analytical and operational skills with an ability to identify meaningful insights from complex data.

• Self-starter who thrives in ambiguity in a fast-paced environment.

• Ability to deliver on end-to-end projects with a high level of autonomy.

PHYSICAL REQUIREMENTS

• This position requires the individual to wear and work in personal protective equipment.

• This position requires that the individual is able to lift a minimum of 25lbs.

• Substantial movements (motions) of the wrists, hands, and/or fingers are required.

• The worker is required to have close visual acuity to perform an activity such as: preparing and analyzing data and figures, writing and reviewing documents, and pipetting small volumes of clear liquids.

Compensation & Total Rewards

This range reflects a good-faith estimate of the

Prepare for the interview

Nothing collected for this employer yet. The Blind 75 is what technical screens draw from; practise it here, with a coach, in Java or Python.

More at Natera

All open software jobs